LAMA2 CLIA Kit for Human(Homo sapiens) | EIAab.comLAMA2 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > LAMA2(Gene name) > Human

LAMA2 (Gene name),

Laminin subunit alpha-2 (Protein name ), LAMA2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LAMA2(LAMM);

Protein name:

Laminin subunit alpha-2;

Alternative:

Laminin-12 subunit alpha;Laminin M chain;Laminin-4 subunit alpha;Laminin-2 subunit alpha;Merosin heavy chain;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-2 is a subunit of laminin-2 (laminin-211 or merosin), laminin-4 (laminin-221 or S-merosin) and laminin-12 (laminin-213). Interacts with FBLN1, FBLN2 and NID2.

Function:

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane Major component.

Protein Attributes:

Sequence length:

3122

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3122:

LEVNFAKALE | LRGVQPVSCP | AN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P24043

STRING:

9606.ENSP00000400365

SMR:

P24043

MIM:

156225

KEGG:

hsa:3908

Pfam:

PF00052

UniGene:

Hs.200841

Uniprot:

P24043

FOR

ELISA Kit for Human Laminin subunit alpha-2

Cat.:

E9489h

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Manual:

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Packing:

96T

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ELISA Kit for Human Laminin subunit alpha-2

Cat.:

E9489m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Laminin subunit alpha-2

Cat.:

U9489m

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MSDS:

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Packing:

96T

CLIA Kit for Human Laminin subunit alpha-2

Cat.:

U9489h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Laminin subunit alpha-2

Cat.:

P9489Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Laminin subunit alpha-2

Cat.:

P9489Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Laminin subunit alpha-2

Protein for Human Laminin subunit alpha-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human laminin M chain (merosin): complete primary structure, chromosomal assignment, and expression of the M and A chain in human fetal tissues."
Vuolteenaho R. , Nissinen M. , Sainio K. , Byers M. , Eddy R. , Hirvonen H. , Shows T.B. , Sariola H. , Engvall E. , Tryggvason K.
J. Cell Biol.124:381-394(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-2587
tissue: Placenta.
2.

"Structure of the human laminin alpha2-chain gene (LAMA2), which is affected in congenital muscular dystrophy."
Zhang X. , Vuolteenaho R. , Tryggvason K.
J. Biol. Chem.271:27664-27669(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-2587
3.

"The DNA sequence and analysis of human chromosome 6."
Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Human laminin M chain: epitope analysis of its monoclonal antibodies by immunoscreening of cDNA clones and tissue expression."
Hori H. , Kanamori T. , Mizuta T. , Yamaguchi N. , Liu Y. , Nagai Y.
J. Biochem.116:1212-1219(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1360-3122
5.

"Merosin, a tissue-specific basement membrane protein, is a laminin-like protein."
Ehrig K. , Leivo I. , Argraves W.S. , Ruoslahti E. , Engvall E.
Proc. Natl. Acad. Sci. U.S.A.87:3264-3268(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1981-3122;PARTIAL PROTEIN SEQUENCE;VARIANT VAL-2587
tissue: Placenta.
6.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-363
tissue: Plasma.
7.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1901; ASN-1916; ASN-1920; ASN-2017 AND ASN-2648
tissue: Liver.
8.

"Novel single base polymorphisms and rare sequence variants in the laminin 2-chain coding region detected by RNA/SSCP analysis."
Panicker S.G. , Mendell J.T. , Chen L. , Feng B. , Sahenk Z. , Marzluf G.A. , Amato A.A. , Mendell J.R.
Hum. Mutat.13:174-174(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GLN-545; HIS-619; LEU-919; HIS-2586 AND LYS-2614
9.

Panicker S.G. , Mendell J.T. , Chen L. , Feng B. , Sahenk Z. , Marzluf G.A. , Amato A.A. , Mendell J.R.
Hum. Mutat.13:340-340(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
10.

"Congenital muscular dystrophy with primary partial laminin alpha-2 chain deficiency: molecular study."
He Y. , Jones K.J. , Vignier N. , Morgan G. , Chevallay M. , Barois A. , Estournet-Mathiaud B. , Hori H. , Mizuta T. , Tome F.M.S. , North K.N. , Guicheney P.
Neurology57:1319-1322(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MDC1A PRO-2564
11.

"Clinical and molecular study in congenital muscular dystrophy with partial laminin alpha-2 (LAMA2) deficiency."
Tezak Z. , Prandini P. , Boscaro M. , Marin A. , Devaney J. , Marino M. , Fanin M. , Trevisan C.P. , Park J. , Tyson W. , Finkel R. , Garcia C. , Angelini C. , Hoffman E.P. , Pegoraro E.
Hum. Mutat.21:103-111(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MDC1A TYR-527 AND ARG-862
12.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ALA-1160

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